Uric acid (2,6,8 Trioxypurine ,Urate)

Sample type:

• Serum

• Plasma(lithium heparin)

Uses:-

• useful in the diagnosis and treatment of gout, renal failure, and a variety of other disorders including leukemia, psoriasis, starvation, and other wasting conditions.

• Monitor chemotherapeutic treatment of neoplasms to avoid renal urate deposition with possible renal failure (tumor lysis syndrome)

Precautions:-

• No special precautions.

Interfering factors:

• Methodologic interference

• A purine-rich diet (liver, kidney, sweetbread) as well as severe exercise, increases uric acid values

• Drugs causing increased uric acid concentration include diuretics, pyrazinamide, ethambutol, and nicotinic acid. Drugs causing increased uric acid concentration include diuretics, pyrazinamide, ethambutol, and nicotinic acid.

Pre analytical errors:-

1. Unlabeled or mislabeled specimen.

The corrective action

1. Reject the sample and another one is requested.

Post analytical errors:-

1. Write wrong name on the report.

2. Send wrong results to the patient.

The corrective action

1. make sure that the name and all data are right

2. Communicate to the patient and apologize for this mistake and sent the right report to him.

Referance range :-

• Male: 2.5–8.0 mg/dL

• Female: 1.9–7.5 mg/dL