Myeloperoxidase
(MBO)

Sample type

Serum

Uses

1-Marker of inflammation when elevated in plasma. MPO may be used for the evaluation of patients presenting with acute chest pain, in conjunction with ECG and cardiac biomarkers.

2-Evaluating patients suspected of having immune-mediated vasculitis, especially microscopic polyangiitis (MPA), when used in conjunction with other autoantibody tests

Precautions

No special precaution required

Interferring factor

1-It has been demonstrated that elevations of MPO can occur with the administration of heparin products, potentially confounding its accuracy.

2-Elevated in rheumatoid arthritis.

Pre analytical error

Taking heparin and autoimmune disease (Rheumatoid arthritis) raise the MPO

Corrective action

Taking medical history of the patient and their medications.

Post-analytical errors

1-Writing a wrong result or wrong name in the report

2-report were sent to incorrect patient

The corrective actions

1- If the report is not delivered to the patient and this error is discovered the correct result or the correct name must be written, but if the report is delivered to the patient must communicate with him and tell him that an error has occurred and replace with the correct report.

2-Communicate with patient ,apologizing for the error, and providing him with the correct report.

Reference range

<0.4 U (negative)

0.4-0.9 U (equivocal)

> or =1.0 U (positive)