β2-Microglobulin
(β2M)

Sample type:

Serum.

Test use:

Evaluate the severity and prognosis of multiple myeloma, chronic lymphocytic leukemia, or non-Hodgkin’s lymphoma; detect kidney damage and distinguish between glomerular and tubular kidney disorders.

Precautions:

You don’t need any special preparations for a CSF analysis, but you may be asked to empty your bladder and bowels before the test.

Interfering factors:

Drugs such as lithium, cyclosporine, cisplatin, carboplatin, and aminoglycoside antibiotics can increase β2-microglobulin concentrations.

Pre analytical errors:

1) Gross hemolysis.

2) Unlabelled sample.

3) Improper sample preparation.

Post analytical errors:

1) Delayed report.

2) You may be instructed not to eat (fast) six hours before the test.

Corrective actions:

Rejecting a hemolysed sample and take new sample.