Infliximab and Anti-Infliximab Antibody
(IFX , Anti – IFX)

Sample type:

serum

Uses:

provide infliximab drug concentratiom levels as well as levels of anti – infliximab antibodies.

Precaution :

Patient Preparation:

For 12 hours before specimen collection do not take multivitamins or dietary supplements containing biotin (vitamin B7)

sample collection:

A blood sample drawn from a vein for testing

Interfering factor :

1. Hemolysed, icteric, lipemic or microbially contaminated sera or plasma are not recommended for testing

2. Taking multivitamins or dietary supplements containing biotin (vitamin B7) interrupt the result .

Pre - analytical errors:

Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens.

Corrective action :

Proper sample collection and handling

Post analytical errors:

1- Writing wrong name in the report

2- Writing a wrong result in the report

The corrective action

1/Make sure you write the correct name in the report or use codes that contain all patient data .

2/If the report is not delivered to the patient and this error is discovered the correct result must be written, but if the report is delivered to the patient must communicate with him and tell him that an error has occurred and replace with the correct report

Reference ranges:

Infliximab Drug Levels

3 – 6 micrograms per ml

Anti-Infliximab Antibodies

Negative <10 nanograms/ml

Positive >10 nanograms/ml