Gastrin
Sample type
Serum
Uses
Diagnose Zollinger-Ellison (Z-E) syndrome; diagnose gastrinoma. Gastrin with gastric acid hypersecretion (basal acid secretion5 mmol/hour in a patient with peptic ulcer who has not had surgery)
establishes unequivocally the diagnosis of the Zollinger-Ellison
syndrome.
Antral G-cell hyperplasia may relate to high gastrin levels and duodenal ulcer
Precautions
The patient must be fasting overnight, 12 to 14 hours
Interfering factors
Gross hemolysis; patient not fasting; specimen not received frozen; gross lipemia; plasma specimen
Pre-analytical errors
Forget frozen sample
Forget tell patient he needs to fast for 12 hours beforehand.
The corrective action
Frozen sample
Tell patient he needs to fast for 12 hours beforehand.
Post-analytical errors
Write an other patient`s name in the report
The corrective action
If the report is not delivered to the patient and this error is discovered, the correct name must be written, but if the report is delivered to the patient, you must communicate with him, apologise to him, and tell him that an error has occurred and replace it with the correct report
Reference range
Adults and Pediatric
-
0 to 1 month: 69−190 pg/mL
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2 to 22 months: 55−186 pg/mL
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22 months to 16 years:
-
Fasting 3 to 4 hours: 2−168 pg/mL
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Fasting 5 to 6 hours: 3−117 pg/mL
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Fasting >8 hours: 1−125 pg/mL
-
-
Older than 16 years: 0−115 pg/mL