CSF Myelin basic protein
(MBP)

Sample Type

Cerebrospinal fluid

• Uses

1. Assist in diagnosing multiple sclerosis.

2. Determine whether an MS patient is having an active demyelinating episode.

3. diagnose acute brain tissue destruction in children.

• Precautions

Lumbar puncture should be performed within five days of onset of neurologic symptoms suggestive of multiple sclerosis.

• Interfering factors

1. Hemolysis is associated with falsely-elevated levels of MBP.

2. The MBP level may be low to undetectable between attacks.

Results should not be used as a diagnostic procedure without confirmation of the diagnosis by another medically established diagnostic product.

• Pre Analytical Errors

1. Errors in patient preparation,

2. Errors in sample collection.

• Corrective action

1. Preparing the patient before test.

2. Correct sample collection.

• Post analytical errors

1. Failure to report test results.

2. delay in reporting.

• Corrective actions

• Review the report before submitting it, but if the report is delivered to the patient must inform him of the right.