Creatinin in Urine

Sample type

Urine (24-hour)

Uses

Determine creatinuria; increased urine creatine values may be obtained from diseases that reduce muscle mass, including fasting, muscular dystrophy, poliomyelitis, atrophy, inflammatory destructive muscle disease as polymyositis, hyperthyroidism, as well as corticosteroid induced myopathy

Precautions

Instruct the patient to void at 8 AM and discard the specimen. Then collect all the urine, including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Measure and record on the test request form the 24-hour total volume. Mix well. Transfer the urine into transpak frozen purple tube and Label the container with the patient’s name, date, and time collection started and finished. The specimen should be frozen immediately and maintained frozen until tested.

Interfering factors

Thawed specimen; 6N HCl, boric acid, or alkali added to collection (Acid or alkali preservative will convert creatine to creatinine, falsely lowering creatine values.)

Pre_analytical errors

Forget collect the sample for 24 h .

The corrective action

The specimen voided at the end of the 24-hour collection period

Post-analytical errors

Write another patient’s name in the report

The corrective action

If the report is not delivered to the patient and this error is discovered, the correct name must be written, but if the report is delivered to the patient, you must communicate with him, apologise to him, and tell him that an error has occurred and replace it with the correct report

Reference range

Male: 0−40 mg/24 hours; female: 0−80 mg/24 hours