Creatine Kinase Isoenzymes
(CK-BB, CK-MM, CK-MB)

Sample type:

Serum

Uses:

CK isozymes provide more specific information about injured tissue.

CK-MM is useful in skeletal muscle diseases, such as muscle dystrophy, CK-MB in acute myocardial infarction (AMI), and CK-BB in brain damage and malignant tumor.

Precuations:

State the patient’s sex on the test request form.

Interfering factors.

Intense physical exercise can increase CK-MB level.

Preanlytical errors:

Errors in collecting the sample.

Doing exercise before the test.

Corrective action:

Collect the sample on the right tube.

Avoid doing exercise before the test.

Postanalytical errors:

Delay in reporting.

Corrective action:

Avoid the delay in reporting.

Reference range :

CK-MM: 97% to 100%

CK-MB: 0% to 3%

CK-BB: 0%