CCP antibodies

Sample type

Specimen type: Serum (Blood Sample)

Uses

Anti-CCP test is ordered to detect rheumatoid arthritis and helps identify the type of arthritis and asses the prognosis with rheumatoid arthritis.

Precautions

Be sure to tell your health care provider about all medicines, vitamins, and dietary supplements you are taking. Your practitioner will determine if you need to stop taking any of them before the test.

Interfering factors

1. Smoking increases the risk of testing positive for anti-CCP antibody levels and is also associated with higher levels and more severe disease status in Rheumatoid Arthritis patients .

2. Vitamin D may help lower anti-CCP antibodies by suppressing overactive immune cells that attack the body’s own proteins and tissues .

3. In case studies, higher omega-3 fatty acid levels are associated with a lower risk of anti-CCP antibody production .

Pre analytical errors

1- If the sample (serum) was not collected and stored with the correct instructions ,it will affect the result .

Corrective action

Follow the instructions of serum Sample collection protocol ( certification, incubation and temperature of storage) .

Post analytical errors

1. Delayed and wrong results.

Corrective action

1. The results must be read back to lab personnel to verify that no errors has occurred in the verbal communication .

Reference range

Negative: <7 U/mL or <20 U

Weak positive: 7-10 U/mL or 20-39 U

Positive: >10 U/mL or 40-59 U

Strong positive: > or = 60 U