Anti Basal Ganglia Antibodies
(ABGA)

- Sample Type

(Serum)

- Uses

1) Anti-basal ganglia antibodies (ABGA) have been associated with movement disorders and psychiatric disturbances in children. These include: Sydenham’s chorea (prototype); tics (PANDAS) and a subset of cases with Tourette’s syndrome (TS).

2) ABGA may also be detected, on rare occasions, in patients with adult-onset tics, dystonia and in some cases with post-encephalitic Parkinsonism or encephalitis lethargic (EL) Anti-NMDA receptor antibodies have also been associated with EL.

- Precautions

1. Plasma isn’t acceptable

2. Centrifuge sample and separate the serum within 2 hours

- Interfering factors

age

- Pre Analytical Errors

1. wrong or missing identification,

2. haemolysed, clotted, and insufficient samples,

3. inappropriate blood to anticoagulant ratio, and

4. inappropriate transport and storage conditions.

- Post Analytical Errors

1) Write another patient’s name in the report.

2) Writing a wrong result in the report.

- Corrective action

1. Rejecting any sample with anticoagulant

2. Review the report before submitting it, but if the report is delivered to the patient must inform him of the right