11-Deoxycortisol ( cortodoxone, corticosterone and compound S )
Sample type: -
Serum, frozen
Uses: -
1- Diagnosis of and monitoring therapeutic response in CAH due to 11 &bgr; -hydroxylase deficiency.
2- Assessment of adrenal response in the metyrapone test; result after metyrapone stimulation is greater than 8000 ng/dL.
3- Evaluate hypothalamic-pituitary-adrenal axis and pituitary ACTH reserve.
Precaution: -
No isotopes administered 24 hours prior to venipuncture.
Interfere factor: -
Patients with myxedema, some pregnant patients, and those on oral contraceptives respond poorly during the test.
Pre analytical error: -
Citrate plasma specimen; improper labeling.
Corrective action: -
Serum sample should be used.
Check for labeling.
Post analytical error: -
Reports were sent to the incorrect patient
Corrective action: -
Communicate with patient, apologizing for the error, and providing him with the correct report.
Reference range: -
-
<50 ng/dLin males.
-
<33 ng/dLin females.