1,5-Anhydroglucitol
(1,5-AG)
Sample type: -
Serum or plasma (EDTA)
Uses: -
1- Used clinically to monitor short-term glycemic control in patients with diabetes (1–2 weeks).
2- Useful marker for postprandial hyperglycemia.
3- Performs better than hemoglobin A1C for monitoring glucose profile in pregnancies complicated by type 1 diabetes.
Precautions: -
No specific precautions need.
Interfere factor: -
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In patients with poorly controlled DM, 1,5-AG is less sensitive to modest changes in glycemic control because of continuous glycosuria.
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Levels can be influenced by factors such as dairy product, races, uric acid, triglycerides, liver disease, gastrectomy state, and cystic fibrosis.
Pre analytical errors: -
- If the sample was not collected with the correct instructions, or you received unlabeled sample.
Corrective action: -
- The sample should be rejected, and another sample requested.
Post analytical error: -
- Incorrect calculation
Corrective action: -
-
Should read the pamphlet well, then perform the calculation.
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It is better to perform the calculation more than once to be sure you have the correct result.
Reference range: -
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10.7–32.0 μg/mLin males.
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6.8–29.3 μg/mLin females.
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Glycemic control goal for diabetic patients: >10